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Elevated Vacuolar Uptake of Fluorescently Labeled Antifungal Drug Caspofungin Predicts Echinocandin Resistance in Pathogenic Yeast

[Image: see text] Echinocandins are the newest class of antifungal drugs in clinical use. These agents inhibit β-glucan synthase, which catalyzes the synthesis of β-glucan, an essential component of the fungal cell wall, and have a high clinical efficacy and low toxicity. Echinocandin resistance is...

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Detalles Bibliográficos
Autores principales:	Jaber, Qais Z., Bibi, Maayan, Ksiezopolska, Ewa, Gabaldon, Toni, Berman, Judith, Fridman, Micha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596861/ https://www.ncbi.nlm.nih.gov/pubmed/33145409 http://dx.doi.org/10.1021/acscentsci.0c00813

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