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Sustained androgen receptor signaling is a determinant of melanoma cell growth potential and tumorigenesis
Melanoma susceptibility differs significantly in male versus female populations. Low levels of androgen receptor (AR) in melanocytes of the two sexes are accompanied by heterogeneous expression at various stages of the disease. Irrespective of expression levels, genetic and pharmacological suppressi...
Autores principales: | Ma, Min, Ghosh, Soumitra, Tavernari, Daniele, Katarkar, Atul, Clocchiatti, Andrea, Mazzeo, Luigi, Samarkina, Anastasia, Epiney, Justine, Yu, Yi-Ru, Ho, Ping-Chih, Levesque, Mitchell P., Özdemir, Berna C., Ciriello, Giovanni, Dummer, Reinhard, Dotto, G. Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596884/ https://www.ncbi.nlm.nih.gov/pubmed/33112375 http://dx.doi.org/10.1084/jem.20201137 |
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