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Significant role of magnetic resonance imaging for the diagnosis and evaluation of cardiac amyloidosis in primary light chain amyloidosis
A 47-year-old male with macroglossia presented with dyspnea on effort and chest pain at rest. Cardiac MRI revealed diffuse global subendocardial late gadolinium enhancement below the left ventricular endocardium and a dark blood pool of intracardiac contrast medium. Tongue biopsy revealed amyloid de...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
JSLRT
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596909/ https://www.ncbi.nlm.nih.gov/pubmed/32779613 http://dx.doi.org/10.3960/jslrt.19040 |
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author | Sekiguchi, Yasunobu Wakabayashi, Mutsumi Iizuka, Hiroko Takizawa, Haruko Sugimoto, Keiji Sakajiri, Sakura Inano, Tadaaki Fukuda, Yasutaka Hamano, Yasuharu Tomita, Shigeki Izumi, Hiroshi Isogai, Hiroyuki Okubo, Mitsuo Nakamura, Noriko Sawada, Tomohiro Matsumoto, Kimihiro Noguchi, Masaaki |
author_facet | Sekiguchi, Yasunobu Wakabayashi, Mutsumi Iizuka, Hiroko Takizawa, Haruko Sugimoto, Keiji Sakajiri, Sakura Inano, Tadaaki Fukuda, Yasutaka Hamano, Yasuharu Tomita, Shigeki Izumi, Hiroshi Isogai, Hiroyuki Okubo, Mitsuo Nakamura, Noriko Sawada, Tomohiro Matsumoto, Kimihiro Noguchi, Masaaki |
author_sort | Sekiguchi, Yasunobu |
collection | PubMed |
description | A 47-year-old male with macroglossia presented with dyspnea on effort and chest pain at rest. Cardiac MRI revealed diffuse global subendocardial late gadolinium enhancement below the left ventricular endocardium and a dark blood pool of intracardiac contrast medium. Tongue biopsy revealed amyloid deposition, which was limited in the myocardium. He was diagnosed with primary light chain amyloidosis. His condition was stage I according to the Mayo Clinic staging system. He underwent autologous peripheral blood stem cell transplantation. On Day 10, he developed chest pain and died suddenly on Day 11. Postmortem examination revealed amyloid deposition throughout the heart. |
format | Online Article Text |
id | pubmed-7596909 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | JSLRT |
record_format | MEDLINE/PubMed |
spelling | pubmed-75969092020-11-03 Significant role of magnetic resonance imaging for the diagnosis and evaluation of cardiac amyloidosis in primary light chain amyloidosis Sekiguchi, Yasunobu Wakabayashi, Mutsumi Iizuka, Hiroko Takizawa, Haruko Sugimoto, Keiji Sakajiri, Sakura Inano, Tadaaki Fukuda, Yasutaka Hamano, Yasuharu Tomita, Shigeki Izumi, Hiroshi Isogai, Hiroyuki Okubo, Mitsuo Nakamura, Noriko Sawada, Tomohiro Matsumoto, Kimihiro Noguchi, Masaaki J Clin Exp Hematop Case Report A 47-year-old male with macroglossia presented with dyspnea on effort and chest pain at rest. Cardiac MRI revealed diffuse global subendocardial late gadolinium enhancement below the left ventricular endocardium and a dark blood pool of intracardiac contrast medium. Tongue biopsy revealed amyloid deposition, which was limited in the myocardium. He was diagnosed with primary light chain amyloidosis. His condition was stage I according to the Mayo Clinic staging system. He underwent autologous peripheral blood stem cell transplantation. On Day 10, he developed chest pain and died suddenly on Day 11. Postmortem examination revealed amyloid deposition throughout the heart. JSLRT 2020-08-08 /pmc/articles/PMC7596909/ /pubmed/32779613 http://dx.doi.org/10.3960/jslrt.19040 Text en © 2020 by The Japanese Society for Lymphoreticular Tissue Research https://creativecommons.org/licenses/by-nc-sa/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution ShareAlike (CC BY-NC-SA) 4.0 License. |
spellingShingle | Case Report Sekiguchi, Yasunobu Wakabayashi, Mutsumi Iizuka, Hiroko Takizawa, Haruko Sugimoto, Keiji Sakajiri, Sakura Inano, Tadaaki Fukuda, Yasutaka Hamano, Yasuharu Tomita, Shigeki Izumi, Hiroshi Isogai, Hiroyuki Okubo, Mitsuo Nakamura, Noriko Sawada, Tomohiro Matsumoto, Kimihiro Noguchi, Masaaki Significant role of magnetic resonance imaging for the diagnosis and evaluation of cardiac amyloidosis in primary light chain amyloidosis |
title | Significant role of magnetic resonance imaging for the diagnosis and
evaluation of cardiac amyloidosis in primary light chain amyloidosis |
title_full | Significant role of magnetic resonance imaging for the diagnosis and
evaluation of cardiac amyloidosis in primary light chain amyloidosis |
title_fullStr | Significant role of magnetic resonance imaging for the diagnosis and
evaluation of cardiac amyloidosis in primary light chain amyloidosis |
title_full_unstemmed | Significant role of magnetic resonance imaging for the diagnosis and
evaluation of cardiac amyloidosis in primary light chain amyloidosis |
title_short | Significant role of magnetic resonance imaging for the diagnosis and
evaluation of cardiac amyloidosis in primary light chain amyloidosis |
title_sort | significant role of magnetic resonance imaging for the diagnosis and
evaluation of cardiac amyloidosis in primary light chain amyloidosis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596909/ https://www.ncbi.nlm.nih.gov/pubmed/32779613 http://dx.doi.org/10.3960/jslrt.19040 |
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