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Overexpression of OCT-1 gene is a biomarker of adverse prognosis for diffuse large B-cell lymphoma (DLBCL): data from a retrospective cohort of 77 Brazilian patients

BACKGROUND: OCT-1 gene is a member of the POU-homeodomain family of transcriptional regulators of B-lymphocyte differentiation by controlling expression of B-cell specific genes. BCL-2 gene is a potent inhibitor of apoptosis and it is essential during B-cell differentiation into germinal center. The...

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Detalles Bibliográficos
Autores principales: Gouveia, Gisele R., Ferreira, Suzete C., Siqueira, Sheila A. C., de Pádua Covas Lage, Luis Alberto, Hallack Neto, Abrahão E., de Oliveira Costa, Renata, Pereira, Juliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596969/
https://www.ncbi.nlm.nih.gov/pubmed/33121489
http://dx.doi.org/10.1186/s12885-020-07553-2