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Overexpression of OCT-1 gene is a biomarker of adverse prognosis for diffuse large B-cell lymphoma (DLBCL): data from a retrospective cohort of 77 Brazilian patients
BACKGROUND: OCT-1 gene is a member of the POU-homeodomain family of transcriptional regulators of B-lymphocyte differentiation by controlling expression of B-cell specific genes. BCL-2 gene is a potent inhibitor of apoptosis and it is essential during B-cell differentiation into germinal center. The...
Autores principales: | Gouveia, Gisele R., Ferreira, Suzete C., Siqueira, Sheila A. C., de Pádua Covas Lage, Luis Alberto, Hallack Neto, Abrahão E., de Oliveira Costa, Renata, Pereira, Juliana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7596969/ https://www.ncbi.nlm.nih.gov/pubmed/33121489 http://dx.doi.org/10.1186/s12885-020-07553-2 |
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