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Protein kinase function of pyruvate kinase M2 and cancer

Pyruvate kinase is a terminal enzyme in the glycolytic pathway, where it catalyzes the conversion of phosphoenolpyruvate to pyruvate and production of ATP via substrate level phosphorylation. PKM2 is one of four isoforms of pyruvate kinase and is widely expressed in many types of tumors and associat...

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Detalles Bibliográficos
Autores principales: Chen, Xun, Chen, Shangwu, Yu, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7597019/
https://www.ncbi.nlm.nih.gov/pubmed/33292198
http://dx.doi.org/10.1186/s12935-020-01612-1

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