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Histopathological and immunohistochemical characterization of testicular T-cell lymphoma in a dog
Canine lymphoma is the most common neoplasm of the hematopoietic system with the most frequently diagnosed malignancy. Also, dogs affected by T-cell lymphoma displayed a lower rate of complete chemotherapy response and have a high risk of death in the early stage of the disease. A 5-year-old male mi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Urmia University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7597786/ https://www.ncbi.nlm.nih.gov/pubmed/33133469 http://dx.doi.org/10.30466/vrf.2020.111869.2656 |
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author | Namazi, Fatemeh Shojaee Tabrizi, Aidin Zarei Kordshouli, Forough |
author_facet | Namazi, Fatemeh Shojaee Tabrizi, Aidin Zarei Kordshouli, Forough |
author_sort | Namazi, Fatemeh |
collection | PubMed |
description | Canine lymphoma is the most common neoplasm of the hematopoietic system with the most frequently diagnosed malignancy. Also, dogs affected by T-cell lymphoma displayed a lower rate of complete chemotherapy response and have a high risk of death in the early stage of the disease. A 5-year-old male mixed dog was presented to the Small Animal Hospital, School of Veterinary Medicine, Shiraz University, Shiraz, Iran with a history of left testicle swelling for four months. The testicle had approximately 13.00×10.00 cm size with a greyish-white cut surface. Histopathologically, the testicular tissue was infiltrated by neoplastic cells as only a few degenerated seminiferous tubules have remained. The neoplastic cells were round to oval with pleomorphic nuclei and single or multiple prominent nucleoli. Immunohistochemical analysis revealed positive and negative immunoreactivity for CD3 and CD20, respectively. According to histopathological and immunohistochemical features, the tumor was concluded as a testicular T-cell lymphoma. It seems that recognition of lymphoma type could be helpful for clinicians therapeutic protocols. |
format | Online Article Text |
id | pubmed-7597786 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Urmia University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-75977862020-10-31 Histopathological and immunohistochemical characterization of testicular T-cell lymphoma in a dog Namazi, Fatemeh Shojaee Tabrizi, Aidin Zarei Kordshouli, Forough Vet Res Forum Clinical Report Canine lymphoma is the most common neoplasm of the hematopoietic system with the most frequently diagnosed malignancy. Also, dogs affected by T-cell lymphoma displayed a lower rate of complete chemotherapy response and have a high risk of death in the early stage of the disease. A 5-year-old male mixed dog was presented to the Small Animal Hospital, School of Veterinary Medicine, Shiraz University, Shiraz, Iran with a history of left testicle swelling for four months. The testicle had approximately 13.00×10.00 cm size with a greyish-white cut surface. Histopathologically, the testicular tissue was infiltrated by neoplastic cells as only a few degenerated seminiferous tubules have remained. The neoplastic cells were round to oval with pleomorphic nuclei and single or multiple prominent nucleoli. Immunohistochemical analysis revealed positive and negative immunoreactivity for CD3 and CD20, respectively. According to histopathological and immunohistochemical features, the tumor was concluded as a testicular T-cell lymphoma. It seems that recognition of lymphoma type could be helpful for clinicians therapeutic protocols. Urmia University Press 2020 2020-09-15 /pmc/articles/PMC7597786/ /pubmed/33133469 http://dx.doi.org/10.30466/vrf.2020.111869.2656 Text en © 2020 Urmia University. All rights reserved This is an open-access article distributed under the terms of the Creative Commons Attribution-noncommercial 4.0 International License, (https://creativecommons.org/licenses/by-nc/4.0/) which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly. |
spellingShingle | Clinical Report Namazi, Fatemeh Shojaee Tabrizi, Aidin Zarei Kordshouli, Forough Histopathological and immunohistochemical characterization of testicular T-cell lymphoma in a dog |
title | Histopathological and immunohistochemical characterization of testicular T-cell lymphoma in a dog |
title_full | Histopathological and immunohistochemical characterization of testicular T-cell lymphoma in a dog |
title_fullStr | Histopathological and immunohistochemical characterization of testicular T-cell lymphoma in a dog |
title_full_unstemmed | Histopathological and immunohistochemical characterization of testicular T-cell lymphoma in a dog |
title_short | Histopathological and immunohistochemical characterization of testicular T-cell lymphoma in a dog |
title_sort | histopathological and immunohistochemical characterization of testicular t-cell lymphoma in a dog |
topic | Clinical Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7597786/ https://www.ncbi.nlm.nih.gov/pubmed/33133469 http://dx.doi.org/10.30466/vrf.2020.111869.2656 |
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