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Delivery Approaches for Therapeutic Genome Editing and Challenges

Impressive therapeutic advances have been possible through the advent of zinc-finger nucleases and transcription activator-like effector nucleases. However, discovery of the more efficient and highly tailorable clustered regularly interspaced short palindromic repeats (CRISPR) and associated protein...

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Detalles Bibliográficos
Autores principales: Ates, Ilayda, Rathbone, Tanner, Stuart, Callie, Bridges, P. Hudson, Cottle, Renee N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7597956/
https://www.ncbi.nlm.nih.gov/pubmed/32977396
http://dx.doi.org/10.3390/genes11101113