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Tick-Borne Flaviviruses Depress AKT Activity during Acute Infection by Modulating AKT1/2

Tick-borne flaviviruses (TBFVs) are reemerging public health threats. To develop therapeutics against these pathogens, increased understanding of their interactions with the mammalian host is required. The PI3K-AKT pathway has been implicated in TBFV persistence, but its role during acute virus infe...

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Detalles Bibliográficos
Autores principales: Kirsch, Joshua M., Mlera, Luwanika, Offerdahl, Danielle K., VanSickle, Marthe, Bloom, Marshall E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598186/
https://www.ncbi.nlm.nih.gov/pubmed/32977414
http://dx.doi.org/10.3390/v12101059