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Cardiac Involvement In Multiorgan Sarcoidosis: Prognostic and Therapeutic Implications
Sarcoidosis is a systemic granulomatous disease with a highly variable clinical impact. Accurate prognostic evaluation is fundamental to establish the best therapeutic approach. Multiorgan disease and especially the involvement of vital organs, such as the heart, are associated with worse outcomes a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598214/ https://www.ncbi.nlm.nih.gov/pubmed/33145123 http://dx.doi.org/10.7759/cureus.10714 |
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author | Higueruela-Mínguez, Cecilia Martín-García, Ana Chamorro, Antonio J Marcos, Miguel Ragozzino, Silvio |
author_facet | Higueruela-Mínguez, Cecilia Martín-García, Ana Chamorro, Antonio J Marcos, Miguel Ragozzino, Silvio |
author_sort | Higueruela-Mínguez, Cecilia |
collection | PubMed |
description | Sarcoidosis is a systemic granulomatous disease with a highly variable clinical impact. Accurate prognostic evaluation is fundamental to establish the best therapeutic approach. Multiorgan disease and especially the involvement of vital organs, such as the heart, are associated with worse outcomes and often require more aggressive therapy. Here, we describe the case of a young adult with sarcoidosis with lymph node, pulmonary, hepatosplenic, and cardiac involvement. This clinical scenario emphasizes the importance of a thorough prognostic assessment and highlights some of the main unmet clinical needs for the risk stratification and management of these patients. |
format | Online Article Text |
id | pubmed-7598214 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-75982142020-11-02 Cardiac Involvement In Multiorgan Sarcoidosis: Prognostic and Therapeutic Implications Higueruela-Mínguez, Cecilia Martín-García, Ana Chamorro, Antonio J Marcos, Miguel Ragozzino, Silvio Cureus Cardiology Sarcoidosis is a systemic granulomatous disease with a highly variable clinical impact. Accurate prognostic evaluation is fundamental to establish the best therapeutic approach. Multiorgan disease and especially the involvement of vital organs, such as the heart, are associated with worse outcomes and often require more aggressive therapy. Here, we describe the case of a young adult with sarcoidosis with lymph node, pulmonary, hepatosplenic, and cardiac involvement. This clinical scenario emphasizes the importance of a thorough prognostic assessment and highlights some of the main unmet clinical needs for the risk stratification and management of these patients. Cureus 2020-09-29 /pmc/articles/PMC7598214/ /pubmed/33145123 http://dx.doi.org/10.7759/cureus.10714 Text en Copyright © 2020, Higueruela-Mínguez et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Cardiology Higueruela-Mínguez, Cecilia Martín-García, Ana Chamorro, Antonio J Marcos, Miguel Ragozzino, Silvio Cardiac Involvement In Multiorgan Sarcoidosis: Prognostic and Therapeutic Implications |
title | Cardiac Involvement In Multiorgan Sarcoidosis: Prognostic and Therapeutic Implications |
title_full | Cardiac Involvement In Multiorgan Sarcoidosis: Prognostic and Therapeutic Implications |
title_fullStr | Cardiac Involvement In Multiorgan Sarcoidosis: Prognostic and Therapeutic Implications |
title_full_unstemmed | Cardiac Involvement In Multiorgan Sarcoidosis: Prognostic and Therapeutic Implications |
title_short | Cardiac Involvement In Multiorgan Sarcoidosis: Prognostic and Therapeutic Implications |
title_sort | cardiac involvement in multiorgan sarcoidosis: prognostic and therapeutic implications |
topic | Cardiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598214/ https://www.ncbi.nlm.nih.gov/pubmed/33145123 http://dx.doi.org/10.7759/cureus.10714 |
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