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Cardiac Involvement In Multiorgan Sarcoidosis: Prognostic and Therapeutic Implications

Sarcoidosis is a systemic granulomatous disease with a highly variable clinical impact. Accurate prognostic evaluation is fundamental to establish the best therapeutic approach. Multiorgan disease and especially the involvement of vital organs, such as the heart, are associated with worse outcomes a...

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Detalles Bibliográficos
Autores principales: Higueruela-Mínguez, Cecilia, Martín-García, Ana, Chamorro, Antonio J, Marcos, Miguel, Ragozzino, Silvio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598214/
https://www.ncbi.nlm.nih.gov/pubmed/33145123
http://dx.doi.org/10.7759/cureus.10714
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author Higueruela-Mínguez, Cecilia
Martín-García, Ana
Chamorro, Antonio J
Marcos, Miguel
Ragozzino, Silvio
author_facet Higueruela-Mínguez, Cecilia
Martín-García, Ana
Chamorro, Antonio J
Marcos, Miguel
Ragozzino, Silvio
author_sort Higueruela-Mínguez, Cecilia
collection PubMed
description Sarcoidosis is a systemic granulomatous disease with a highly variable clinical impact. Accurate prognostic evaluation is fundamental to establish the best therapeutic approach. Multiorgan disease and especially the involvement of vital organs, such as the heart, are associated with worse outcomes and often require more aggressive therapy. Here, we describe the case of a young adult with sarcoidosis with lymph node, pulmonary, hepatosplenic, and cardiac involvement. This clinical scenario emphasizes the importance of a thorough prognostic assessment and highlights some of the main unmet clinical needs for the risk stratification and management of these patients.
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spelling pubmed-75982142020-11-02 Cardiac Involvement In Multiorgan Sarcoidosis: Prognostic and Therapeutic Implications Higueruela-Mínguez, Cecilia Martín-García, Ana Chamorro, Antonio J Marcos, Miguel Ragozzino, Silvio Cureus Cardiology Sarcoidosis is a systemic granulomatous disease with a highly variable clinical impact. Accurate prognostic evaluation is fundamental to establish the best therapeutic approach. Multiorgan disease and especially the involvement of vital organs, such as the heart, are associated with worse outcomes and often require more aggressive therapy. Here, we describe the case of a young adult with sarcoidosis with lymph node, pulmonary, hepatosplenic, and cardiac involvement. This clinical scenario emphasizes the importance of a thorough prognostic assessment and highlights some of the main unmet clinical needs for the risk stratification and management of these patients. Cureus 2020-09-29 /pmc/articles/PMC7598214/ /pubmed/33145123 http://dx.doi.org/10.7759/cureus.10714 Text en Copyright © 2020, Higueruela-Mínguez et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Higueruela-Mínguez, Cecilia
Martín-García, Ana
Chamorro, Antonio J
Marcos, Miguel
Ragozzino, Silvio
Cardiac Involvement In Multiorgan Sarcoidosis: Prognostic and Therapeutic Implications
title Cardiac Involvement In Multiorgan Sarcoidosis: Prognostic and Therapeutic Implications
title_full Cardiac Involvement In Multiorgan Sarcoidosis: Prognostic and Therapeutic Implications
title_fullStr Cardiac Involvement In Multiorgan Sarcoidosis: Prognostic and Therapeutic Implications
title_full_unstemmed Cardiac Involvement In Multiorgan Sarcoidosis: Prognostic and Therapeutic Implications
title_short Cardiac Involvement In Multiorgan Sarcoidosis: Prognostic and Therapeutic Implications
title_sort cardiac involvement in multiorgan sarcoidosis: prognostic and therapeutic implications
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598214/
https://www.ncbi.nlm.nih.gov/pubmed/33145123
http://dx.doi.org/10.7759/cureus.10714
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