Are there pulmonary sequelae in patients recovering from COVID-19?

It has been recently hypothesized that infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may lead to fibrotic sequelae in patients recovering from coronavirus disease 2019 (COVID-19). In this observational study, hospitalized patients with COVID-19 had a HRCT of the chest per...

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Autores principales: Rogliani, Paola, Calzetta, Luigino, Coppola, Angelo, Puxeddu, Ermanno, Sergiacomi, Gianluigi, D’Amato, Dejanira, Orlacchio, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598236/
https://www.ncbi.nlm.nih.gov/pubmed/33126869
http://dx.doi.org/10.1186/s12931-020-01550-6
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author Rogliani, Paola
Calzetta, Luigino
Coppola, Angelo
Puxeddu, Ermanno
Sergiacomi, Gianluigi
D’Amato, Dejanira
Orlacchio, Antonio
author_facet Rogliani, Paola
Calzetta, Luigino
Coppola, Angelo
Puxeddu, Ermanno
Sergiacomi, Gianluigi
D’Amato, Dejanira
Orlacchio, Antonio
author_sort Rogliani, Paola
collection PubMed
description It has been recently hypothesized that infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may lead to fibrotic sequelae in patients recovering from coronavirus disease 2019 (COVID-19). In this observational study, hospitalized patients with COVID-19 had a HRCT of the chest performed to detect the extension of fibrotic abnormalities via Hounsfield Units (HU). At follow-up, the lung density significantly improved in both lungs and in each lobe of all patients, being in the normal range (− 950 to − 700 HU). This study provides preliminary evidence that hospitalized patients with mild-to-moderate forms of COVID-19 are not at risk of developing pulmonary fibrosis.
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spelling pubmed-75982362020-11-02 Are there pulmonary sequelae in patients recovering from COVID-19? Rogliani, Paola Calzetta, Luigino Coppola, Angelo Puxeddu, Ermanno Sergiacomi, Gianluigi D’Amato, Dejanira Orlacchio, Antonio Respir Res Letter to the Editor It has been recently hypothesized that infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may lead to fibrotic sequelae in patients recovering from coronavirus disease 2019 (COVID-19). In this observational study, hospitalized patients with COVID-19 had a HRCT of the chest performed to detect the extension of fibrotic abnormalities via Hounsfield Units (HU). At follow-up, the lung density significantly improved in both lungs and in each lobe of all patients, being in the normal range (− 950 to − 700 HU). This study provides preliminary evidence that hospitalized patients with mild-to-moderate forms of COVID-19 are not at risk of developing pulmonary fibrosis. BioMed Central 2020-10-30 2020 /pmc/articles/PMC7598236/ /pubmed/33126869 http://dx.doi.org/10.1186/s12931-020-01550-6 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Letter to the Editor
Rogliani, Paola
Calzetta, Luigino
Coppola, Angelo
Puxeddu, Ermanno
Sergiacomi, Gianluigi
D’Amato, Dejanira
Orlacchio, Antonio
Are there pulmonary sequelae in patients recovering from COVID-19?
title Are there pulmonary sequelae in patients recovering from COVID-19?
title_full Are there pulmonary sequelae in patients recovering from COVID-19?
title_fullStr Are there pulmonary sequelae in patients recovering from COVID-19?
title_full_unstemmed Are there pulmonary sequelae in patients recovering from COVID-19?
title_short Are there pulmonary sequelae in patients recovering from COVID-19?
title_sort are there pulmonary sequelae in patients recovering from covid-19?
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598236/
https://www.ncbi.nlm.nih.gov/pubmed/33126869
http://dx.doi.org/10.1186/s12931-020-01550-6
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