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c-Jun N-Terminal Kinase as a Therapeutic Target in Experimental Autoimmune Encephalomyelitis

c-Jun N-terminal kinase (JNK) is upregulated during multiple sclerosis relapses and at the peak of experimental autoimmune encephalomyelitis (EAE). We aim to investigate the effects of pharmacological pan-JNK inhibition on the course of myelin oligodendrocyte glycoprotein (MOG(35-55)) EAE disease us...

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Detalles Bibliográficos
Autores principales: Bagnoud, Maud, Briner, Myriam, Remlinger, Jana, Meli, Ivo, Schuetz, Sara, Pistor, Maximilian, Salmen, Anke, Chan, Andrew, Hoepner, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598244/
https://www.ncbi.nlm.nih.gov/pubmed/32977663
http://dx.doi.org/10.3390/cells9102154