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A preparative chiral separation of hydroxychloroquine using supercritical fluid chromatography
A robust supercritical chromatography (SFC) method using an Enantiocel C2–5 column was developed for the multigram separation of the enantiomers of hydroxychloroquine (HCQ), affirming its use as a scalable technology and ability to provide quantities of each enantiomer for clinical evaluation. The e...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier B.V.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598365/ https://www.ncbi.nlm.nih.gov/pubmed/33166894 http://dx.doi.org/10.1016/j.chroma.2020.461661 |