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Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19

We present an integrated analysis of the clinical measurements, immune cells, and plasma multi-omics of 139 COVID-19 patients representing all levels of disease severity, from serial blood draws collected during the first week of infection following diagnosis. We identify a major shift between mild...

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Detalles Bibliográficos
Autores principales: Su, Yapeng, Chen, Daniel, Yuan, Dan, Lausted, Christopher, Choi, Jongchan, Dai, Chengzhen L., Voillet, Valentin, Duvvuri, Venkata R., Scherler, Kelsey, Troisch, Pamela, Baloni, Priyanka, Qin, Guangrong, Smith, Brett, Kornilov, Sergey A., Rostomily, Clifford, Xu, Alex, Li, Jing, Dong, Shen, Rothchild, Alissa, Zhou, Jing, Murray, Kim, Edmark, Rick, Hong, Sunga, Heath, John E., Earls, John, Zhang, Rongyu, Xie, Jingyi, Li, Sarah, Roper, Ryan, Jones, Lesley, Zhou, Yong, Rowen, Lee, Liu, Rachel, Mackay, Sean, O’Mahony, D. Shane, Dale, Christopher R., Wallick, Julie A., Algren, Heather A., Zager, Michael A., Wei, Wei, Price, Nathan D., Huang, Sui, Subramanian, Naeha, Wang, Kai, Magis, Andrew T., Hadlock, Jenn J., Hood, Leroy, Aderem, Alan, Bluestone, Jeffrey A., Lanier, Lewis L., Greenberg, Philip D., Gottardo, Raphael, Davis, Mark M., Goldman, Jason D., Heath, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598382/
https://www.ncbi.nlm.nih.gov/pubmed/33171100
http://dx.doi.org/10.1016/j.cell.2020.10.037