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DNA supercoiling differences in bacteria result from disparate DNA gyrase activation by polyamines

DNA supercoiling is essential for all living cells because it controls all processes involving DNA. In bacteria, global DNA supercoiling results from the opposing activities of topoisomerase I, which relaxes DNA, and DNA gyrase, which compacts DNA. These enzymes are widely conserved, sharing >91%...

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Detalles Bibliográficos
Autores principales: Duprey, Alexandre, Groisman, Eduardo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598504/
https://www.ncbi.nlm.nih.gov/pubmed/33125364
http://dx.doi.org/10.1371/journal.pgen.1009085