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DNA supercoiling differences in bacteria result from disparate DNA gyrase activation by polyamines
DNA supercoiling is essential for all living cells because it controls all processes involving DNA. In bacteria, global DNA supercoiling results from the opposing activities of topoisomerase I, which relaxes DNA, and DNA gyrase, which compacts DNA. These enzymes are widely conserved, sharing >91%...
Autores principales: | Duprey, Alexandre, Groisman, Eduardo A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598504/ https://www.ncbi.nlm.nih.gov/pubmed/33125364 http://dx.doi.org/10.1371/journal.pgen.1009085 |
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