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Protein Intake and Frailty: A Matter of Quantity, Quality, and Timing

Frailty is a geriatric syndrome that refers to a state of reduced resiliency to stressful events that occurs in response to physiological and/or psychosocial detriments. Frailty is a predictor of poor prognosis, given that frail older adults are at higher risk of many adverse health-related events....

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Autores principales: Coelho-Junior, Hélio J., Marzetti, Emanuele, Picca, Anna, Cesari, Matteo, Uchida, Marco C., Calvani, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598653/
https://www.ncbi.nlm.nih.gov/pubmed/32977714
http://dx.doi.org/10.3390/nu12102915
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author Coelho-Junior, Hélio J.
Marzetti, Emanuele
Picca, Anna
Cesari, Matteo
Uchida, Marco C.
Calvani, Riccardo
author_facet Coelho-Junior, Hélio J.
Marzetti, Emanuele
Picca, Anna
Cesari, Matteo
Uchida, Marco C.
Calvani, Riccardo
author_sort Coelho-Junior, Hélio J.
collection PubMed
description Frailty is a geriatric syndrome that refers to a state of reduced resiliency to stressful events that occurs in response to physiological and/or psychosocial detriments. Frailty is a predictor of poor prognosis, given that frail older adults are at higher risk of many adverse health-related events. Hence, the identification of potential strategies to prevent the development and progression of frailty is of extreme importance for avoiding its negative outcomes. An adequate protein consumption is advocated as a possible intervention for the management of frailty in older adults due to its effects on muscle mass and physical function. However, empirical evidence is still needed to support this proposition. On the other hand, substantial evidence from observational studies has provided important information on the association between frailty and dietary protein-related parameters. Here, we provide a narrative review of the current literature regarding the association between protein intake (amount (how much?), quality (what type?), and distribution across meals (when?)) and frailty-related parameters. The ultimate aim of this work is to offer practical, evidence-based indications to healthcare professionals responsible for the care of frail older adults.
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spelling pubmed-75986532020-10-31 Protein Intake and Frailty: A Matter of Quantity, Quality, and Timing Coelho-Junior, Hélio J. Marzetti, Emanuele Picca, Anna Cesari, Matteo Uchida, Marco C. Calvani, Riccardo Nutrients Review Frailty is a geriatric syndrome that refers to a state of reduced resiliency to stressful events that occurs in response to physiological and/or psychosocial detriments. Frailty is a predictor of poor prognosis, given that frail older adults are at higher risk of many adverse health-related events. Hence, the identification of potential strategies to prevent the development and progression of frailty is of extreme importance for avoiding its negative outcomes. An adequate protein consumption is advocated as a possible intervention for the management of frailty in older adults due to its effects on muscle mass and physical function. However, empirical evidence is still needed to support this proposition. On the other hand, substantial evidence from observational studies has provided important information on the association between frailty and dietary protein-related parameters. Here, we provide a narrative review of the current literature regarding the association between protein intake (amount (how much?), quality (what type?), and distribution across meals (when?)) and frailty-related parameters. The ultimate aim of this work is to offer practical, evidence-based indications to healthcare professionals responsible for the care of frail older adults. MDPI 2020-09-23 /pmc/articles/PMC7598653/ /pubmed/32977714 http://dx.doi.org/10.3390/nu12102915 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Coelho-Junior, Hélio J.
Marzetti, Emanuele
Picca, Anna
Cesari, Matteo
Uchida, Marco C.
Calvani, Riccardo
Protein Intake and Frailty: A Matter of Quantity, Quality, and Timing
title Protein Intake and Frailty: A Matter of Quantity, Quality, and Timing
title_full Protein Intake and Frailty: A Matter of Quantity, Quality, and Timing
title_fullStr Protein Intake and Frailty: A Matter of Quantity, Quality, and Timing
title_full_unstemmed Protein Intake and Frailty: A Matter of Quantity, Quality, and Timing
title_short Protein Intake and Frailty: A Matter of Quantity, Quality, and Timing
title_sort protein intake and frailty: a matter of quantity, quality, and timing
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598653/
https://www.ncbi.nlm.nih.gov/pubmed/32977714
http://dx.doi.org/10.3390/nu12102915
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