Clustering and Fibril Formation during GNNQQNY Aggregation: A Molecular Dynamics Study

The precise kinetic pathways of peptide clustering and fibril formation are not fully understood. Here we study the initial clustering kinetics and transient cluster morphologies during aggregation of the heptapeptide fragment GNNQQNY from the yeast prion protein Sup35. We use a mid-resolution coars...

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Detalles Bibliográficos
Autores principales: Szała-Mendyk, Beata, Molski, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598727/
https://www.ncbi.nlm.nih.gov/pubmed/32987720
http://dx.doi.org/10.3390/biom10101362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598727/
https://www.ncbi.nlm.nih.gov/pubmed/32987720
http://dx.doi.org/10.3390/biom10101362

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