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Clustering and Fibril Formation during GNNQQNY Aggregation: A Molecular Dynamics Study
The precise kinetic pathways of peptide clustering and fibril formation are not fully understood. Here we study the initial clustering kinetics and transient cluster morphologies during aggregation of the heptapeptide fragment GNNQQNY from the yeast prion protein Sup35. We use a mid-resolution coars...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598727/ https://www.ncbi.nlm.nih.gov/pubmed/32987720 http://dx.doi.org/10.3390/biom10101362 |