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Crystal structure of SARS-CoV-2 main protease in complex with the natural product inhibitor shikonin illuminates a unique binding mode
[Figure: see text]
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Science China Press. Published by Elsevier B.V. and Science China Press.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598899/ https://www.ncbi.nlm.nih.gov/pubmed/33163253 http://dx.doi.org/10.1016/j.scib.2020.10.018 |
| _version_ | 1783602744408408064 |
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| author | Li, Jian Zhou, Xuelan Zhang, Yan Zhong, Fanglin Lin, Cheng McCormick, Peter J. Jiang, Feng Luo, Jun Zhou, Huan Wang, Qisheng Fu, Yang Duan, Jingjing Zhang, Jin |
| author_facet | Li, Jian Zhou, Xuelan Zhang, Yan Zhong, Fanglin Lin, Cheng McCormick, Peter J. Jiang, Feng Luo, Jun Zhou, Huan Wang, Qisheng Fu, Yang Duan, Jingjing Zhang, Jin |
| author_sort | Li, Jian |
| collection | PubMed |
| description | [Figure: see text] |
| format | Online Article Text |
| id | pubmed-7598899 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | Science China Press. Published by Elsevier B.V. and Science China Press. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-75988992020-11-02 Crystal structure of SARS-CoV-2 main protease in complex with the natural product inhibitor shikonin illuminates a unique binding mode Li, Jian Zhou, Xuelan Zhang, Yan Zhong, Fanglin Lin, Cheng McCormick, Peter J. Jiang, Feng Luo, Jun Zhou, Huan Wang, Qisheng Fu, Yang Duan, Jingjing Zhang, Jin Sci Bull (Beijing) Short Communication [Figure: see text] Science China Press. Published by Elsevier B.V. and Science China Press. 2021-04-15 2020-10-29 /pmc/articles/PMC7598899/ /pubmed/33163253 http://dx.doi.org/10.1016/j.scib.2020.10.018 Text en © 2020 Science China Press. Published by Elsevier B.V. and Science China Press. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
| spellingShingle | Short Communication Li, Jian Zhou, Xuelan Zhang, Yan Zhong, Fanglin Lin, Cheng McCormick, Peter J. Jiang, Feng Luo, Jun Zhou, Huan Wang, Qisheng Fu, Yang Duan, Jingjing Zhang, Jin Crystal structure of SARS-CoV-2 main protease in complex with the natural product inhibitor shikonin illuminates a unique binding mode |
| title | Crystal structure of SARS-CoV-2 main protease in complex with the natural product inhibitor shikonin illuminates a unique binding mode |
| title_full | Crystal structure of SARS-CoV-2 main protease in complex with the natural product inhibitor shikonin illuminates a unique binding mode |
| title_fullStr | Crystal structure of SARS-CoV-2 main protease in complex with the natural product inhibitor shikonin illuminates a unique binding mode |
| title_full_unstemmed | Crystal structure of SARS-CoV-2 main protease in complex with the natural product inhibitor shikonin illuminates a unique binding mode |
| title_short | Crystal structure of SARS-CoV-2 main protease in complex with the natural product inhibitor shikonin illuminates a unique binding mode |
| title_sort | crystal structure of sars-cov-2 main protease in complex with the natural product inhibitor shikonin illuminates a unique binding mode |
| topic | Short Communication |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598899/ https://www.ncbi.nlm.nih.gov/pubmed/33163253 http://dx.doi.org/10.1016/j.scib.2020.10.018 |
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