Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants

Chronic obstructive pulmonary disease (COPD), diagnosed by reduced lung function, is a leading cause of morbidity and mortality. We performed whole genome sequence (WGS) analysis of lung function and COPD in a multi-ethnic sample of 11,497 participants from population- and family-based studies, and...

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Detalles Bibliográficos
Autores principales: Zhao, Xutong, Qiao, Dandi, Yang, Chaojie, Kasela, Silva, Kim, Wonji, Ma, Yanlin, Shrine, Nick, Batini, Chiara, Sofer, Tamar, Taliun, Sarah A. Gagliano, Sakornsakolpat, Phuwanat, Balte, Pallavi P., Prokopenko, Dmitry, Yu, Bing, Lange, Leslie A., Dupuis, Josée, Cade, Brian E., Lee, Jiwon, Gharib, Sina A., Daya, Michelle, Laurie, Cecelia A., Ruczinski, Ingo, Cupples, L. Adrienne, Loehr, Laura R., Bartz, Traci M., Morrison, Alanna C., Psaty, Bruce M., Vasan, Ramachandran S., Wilson, James G., Taylor, Kent D., Durda, Peter, Johnson, W. Craig, Cornell, Elaine, Guo, Xiuqing, Liu, Yongmei, Tracy, Russell P., Ardlie, Kristin G., Aguet, François, VanDenBerg, David J., Papanicolaou, George J., Rotter, Jerome I., Barnes, Kathleen C., Jain, Deepti, Nickerson, Deborah A., Muzny, Donna M., Metcalf, Ginger A., Doddapaneni, Harshavardhan, Dugan-Perez, Shannon, Gupta, Namrata, Gabriel, Stacey, Rich, Stephen S., O’Connor, George T., Redline, Susan, Reed, Robert M., Laurie, Cathy C., Daviglus, Martha L., Preudhomme, Liana K., Burkart, Kristin M., Kaplan, Robert C., Wain, Louise V., Tobin, Martin D., London, Stephanie J., Lappalainen, Tuuli, Oelsner, Elizabeth C., Abecasis, Goncalo R., Silverman, Edwin K., Barr, R. Graham, Cho, Michael H., Manichaikul, Ani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598941/
https://www.ncbi.nlm.nih.gov/pubmed/33057025
http://dx.doi.org/10.1038/s41467-020-18334-7

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