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Outcomes of Surgical Patch Angioplasty of The Coronary Artery for Diffuse Coronary Artery Disease

INTRODUCTION: Diffuse coronary artery disease (CAD) has a poor prognosis and many patients are ineligible for conventional coronary artery bypass grafting (CABG). This study evaluated the 12-month outcomes of coronary artery reconstruction and surgical patch angioplasty of the coronary artery for di...

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Autores principales: Li, Dong, Guo, Pengfei, Chen, Lei, Wu, Yang, Wang, Gang, Xiao, Cangsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Cirurgia Cardiovascular 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598967/
https://www.ncbi.nlm.nih.gov/pubmed/33118736
http://dx.doi.org/10.21470/1678-9741-2019-0390
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author Li, Dong
Guo, Pengfei
Chen, Lei
Wu, Yang
Wang, Gang
Xiao, Cangsong
author_facet Li, Dong
Guo, Pengfei
Chen, Lei
Wu, Yang
Wang, Gang
Xiao, Cangsong
author_sort Li, Dong
collection PubMed
description INTRODUCTION: Diffuse coronary artery disease (CAD) has a poor prognosis and many patients are ineligible for conventional coronary artery bypass grafting (CABG). This study evaluated the 12-month outcomes of coronary artery reconstruction and surgical patch angioplasty of the coronary artery for diffuse CAD. METHODS: A retrospective cohort study of patients who underwent CABG with surgical patch angioplasty of the coronary artery (reconstruction group) or standard CABG alone (standard group) at the Cardiovascular Surgery Department of the local Hospital between January 2014 and January 2016. Follow-up was censored at 12 months after surgery. RESULTS: Cardiopulmonary bypass and aortic cross-clamping durations were longer in the reconstruction group (n=32) than in the standard group (n=125) (P<0.05). There were no differences in graft blood flow and postoperative levels of cardiac markers between the two groups (P>0.05). In the reconstruction group, one patient died; a vein graft showed occlusion. In the standard group, two patients died; one left internal mammary artery graft and three vein grafts showed occlusion. There were no significant differences in mortality, major adverse cardiovascular and cerebrovascular events, and patency between the two groups (P>0.05). CONCLUSION: Coronary artery reconstruction and surgical patch angioplasty of the coronary artery can be performed for diffuse CAD. Patient outcomes were not significantly different from those of patients who underwent standard CABG.
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spelling pubmed-75989672020-11-04 Outcomes of Surgical Patch Angioplasty of The Coronary Artery for Diffuse Coronary Artery Disease Li, Dong Guo, Pengfei Chen, Lei Wu, Yang Wang, Gang Xiao, Cangsong Braz J Cardiovasc Surg Original Article INTRODUCTION: Diffuse coronary artery disease (CAD) has a poor prognosis and many patients are ineligible for conventional coronary artery bypass grafting (CABG). This study evaluated the 12-month outcomes of coronary artery reconstruction and surgical patch angioplasty of the coronary artery for diffuse CAD. METHODS: A retrospective cohort study of patients who underwent CABG with surgical patch angioplasty of the coronary artery (reconstruction group) or standard CABG alone (standard group) at the Cardiovascular Surgery Department of the local Hospital between January 2014 and January 2016. Follow-up was censored at 12 months after surgery. RESULTS: Cardiopulmonary bypass and aortic cross-clamping durations were longer in the reconstruction group (n=32) than in the standard group (n=125) (P<0.05). There were no differences in graft blood flow and postoperative levels of cardiac markers between the two groups (P>0.05). In the reconstruction group, one patient died; a vein graft showed occlusion. In the standard group, two patients died; one left internal mammary artery graft and three vein grafts showed occlusion. There were no significant differences in mortality, major adverse cardiovascular and cerebrovascular events, and patency between the two groups (P>0.05). CONCLUSION: Coronary artery reconstruction and surgical patch angioplasty of the coronary artery can be performed for diffuse CAD. Patient outcomes were not significantly different from those of patients who underwent standard CABG. Sociedade Brasileira de Cirurgia Cardiovascular 2020 /pmc/articles/PMC7598967/ /pubmed/33118736 http://dx.doi.org/10.21470/1678-9741-2019-0390 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Li, Dong
Guo, Pengfei
Chen, Lei
Wu, Yang
Wang, Gang
Xiao, Cangsong
Outcomes of Surgical Patch Angioplasty of The Coronary Artery for Diffuse Coronary Artery Disease
title Outcomes of Surgical Patch Angioplasty of The Coronary Artery for Diffuse Coronary Artery Disease
title_full Outcomes of Surgical Patch Angioplasty of The Coronary Artery for Diffuse Coronary Artery Disease
title_fullStr Outcomes of Surgical Patch Angioplasty of The Coronary Artery for Diffuse Coronary Artery Disease
title_full_unstemmed Outcomes of Surgical Patch Angioplasty of The Coronary Artery for Diffuse Coronary Artery Disease
title_short Outcomes of Surgical Patch Angioplasty of The Coronary Artery for Diffuse Coronary Artery Disease
title_sort outcomes of surgical patch angioplasty of the coronary artery for diffuse coronary artery disease
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598967/
https://www.ncbi.nlm.nih.gov/pubmed/33118736
http://dx.doi.org/10.21470/1678-9741-2019-0390
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