Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity

Trained innate immunity, induced via modulation of mature myeloid cells or their bone marrow progenitors, mediates sustained increased responsiveness to secondary challenges. Here, we investigated whether anti-tumor immunity can be enhanced through induction of trained immunity. Pre-treatment of mic...

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Detalles Bibliográficos
Autores principales: Kalafati, Lydia, Kourtzelis, Ioannis, Schulte-Schrepping, Jonas, Li, Xiaofei, Hatzioannou, Aikaterini, Grinenko, Tatyana, Hagag, Eman, Sinha, Anupam, Has, Canan, Dietz, Sevina, de Jesus Domingues, Antonio Miguel, Nati, Marina, Sormendi, Sundary, Neuwirth, Ales, Chatzigeorgiou, Antonios, Ziogas, Athanasios, Lesche, Mathias, Dahl, Andreas, Henry, Ian, Subramanian, Pallavi, Wielockx, Ben, Murray, Peter, Mirtschink, Peter, Chung, Kyoung-Jin, Schultze, Joachim L., Netea, Mihai G., Hajishengallis, George, Verginis, Panayotis, Mitroulis, Ioannis, Chavakis, Triantafyllos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599076/
https://www.ncbi.nlm.nih.gov/pubmed/33125892
http://dx.doi.org/10.1016/j.cell.2020.09.058

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