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The cannabinoid ligands SR141716A and AM251 enhance human and mouse islet function via GPR55-independent signalling

AIMS: Endocannabinoids are lipid mediators involved in the regulation of glucose homeostasis. They interact with the canonical cannabinoid receptors CB(1) and CB(2), and it is now apparent that some cannabinoid receptor ligands are also agonists at GPR55. Thus, CB(1) antagonists such as SR141716A, a...

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Detalles Bibliográficos
Autores principales:	Ruz-Maldonado, Inmaculada, Liu, Bo, Atanes, Patricio, Pingitore, Attilio, Huang, Guo Cai, Choudhary, Pratik, Persaud, Shanta J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599183/ https://www.ncbi.nlm.nih.gov/pubmed/31925452 http://dx.doi.org/10.1007/s00018-019-03433-6

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