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Fatty-acid-induced FABP5/HIF-1 reprograms lipid metabolism and enhances the proliferation of liver cancer cells
Hypoxia-inducible factor-1 alpha (HIF-1α) is a transcription factor essential for cancer cell survival. The reprogramming of lipid metabolism has emerged as a hallmark of cancer, yet the relevance of HIF-1α to this process remains elusive. In this study, we profile HIF-1α-interacting proteins using...
Autores principales: | Seo, Jieun, Jeong, Do-Won, Park, Jong-Wan, Lee, Kwang-Woong, Fukuda, Junji, Chun, Yang-Sook |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599230/ https://www.ncbi.nlm.nih.gov/pubmed/33128030 http://dx.doi.org/10.1038/s42003-020-01367-5 |
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