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Fatty-acid-induced FABP5/HIF-1 reprograms lipid metabolism and enhances the proliferation of liver cancer cells

Hypoxia-inducible factor-1 alpha (HIF-1α) is a transcription factor essential for cancer cell survival. The reprogramming of lipid metabolism has emerged as a hallmark of cancer, yet the relevance of HIF-1α to this process remains elusive. In this study, we profile HIF-1α-interacting proteins using...

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Detalles Bibliográficos
Autores principales: Seo, Jieun, Jeong, Do-Won, Park, Jong-Wan, Lee, Kwang-Woong, Fukuda, Junji, Chun, Yang-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599230/
https://www.ncbi.nlm.nih.gov/pubmed/33128030
http://dx.doi.org/10.1038/s42003-020-01367-5

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