Improving read alignment through the generation of alternative reference via iterative strategy

There is generally one standard reference sequence for each species. When extensive variations exist in other breeds of the species, it can lead to ambiguous alignment and inaccurate variant calling and, in turn, compromise the accuracy of downstream analysis. Here, with the help of the FPGA hardwar...

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Detalles Bibliográficos
Autores principales: Bu, Lina, Wang, Qi, Gu, Wenjin, Yang, Ruifei, Zhu, Di, Song, Zhuo, Liu, Xiaojun, Zhao, Yiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599232/
https://www.ncbi.nlm.nih.gov/pubmed/33127969
http://dx.doi.org/10.1038/s41598-020-74526-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599232/
https://www.ncbi.nlm.nih.gov/pubmed/33127969
http://dx.doi.org/10.1038/s41598-020-74526-7

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