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Synthesizing AND gate minigene circuits based on CRISPReader for identification of bladder cancer cells
The logical AND gate gene circuit based on the CRISPR-Cas9 system can distinguish bladder cancer cells from normal bladder epithelial cells. However, the layered artificial gene circuits have the problems of high complexity, difficulty in accurately predicting the behavior, and excessive redundancy,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599332/ https://www.ncbi.nlm.nih.gov/pubmed/33127914 http://dx.doi.org/10.1038/s41467-020-19314-7 |