Histone methyltransferase SET8 is regulated by miR-192/215 and induces oncogene-induced senescence via p53-dependent DNA damage in human gastric carcinoma cells

Gastric cancer (GC) is the most common cancer throughout the world. Despite advances of the treatments, detailed oncogenic mechanisms are largely unknown. In our previous study, we investigated microRNA (miR) expression profiles in human GC using miR microarrays. We found miR-192/215 were upregulate...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaojing, Peng, Yin, Yuan, Yuan, Gao, Yuli, Hu, Fan, Wang, Jian, Zhu, Xiaohui, Feng, Xianling, Cheng, Yulan, Wei, Yanjie, Fan, Xinmin, Xie, Yaohong, Lv, Yansi, Ashktorab, Hassan, Smoot, Duane, Li, Song, Meltzer, Stephen J., Hou, Gangqiang, Jin, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599338/
https://www.ncbi.nlm.nih.gov/pubmed/33127874
http://dx.doi.org/10.1038/s41419-020-03130-4

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