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High G2M Pathway Score Pancreatic Cancer is Associated with Worse Survival, Particularly after Margin-Positive (R1 or R2) Resection

SIMPLE SUMMARY: The G2M checkpoint pathway is a critical step in the cell cycle, which is one of the hallmarks in cancer. We investigated clinical relevance of the G2M pathway in pancreatic cancer, using gene set variation analysis (GSVA) with Hallmark G2M checkpoint gene set. High G2M score tumors...

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Detalles Bibliográficos
Autores principales:	Oshi, Masanori, Newman, Stephanie, Tokumaru, Yoshihisa, Yan, Li, Matsuyama, Ryusei, Endo, Itaru, Katz, Matthew H. G., Takabe, Kazuaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599494/ https://www.ncbi.nlm.nih.gov/pubmed/33036243 http://dx.doi.org/10.3390/cancers12102871

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