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Hypoxia Promotes Mitochondrial Complex I Abundance via HIF-1α in Complex III and Complex IV Deficient Cells

Murine fibroblasts deficient in mitochondria respiratory complexes III (CIII) and IV (CIV) produced by either the ablation of Uqcrfs1 (encoding for Rieske iron sulfur protein, RISP) or Cox10 (encoding for protoheme IX farnesyltransferase, COX10) genes, respectively, showed a pleiotropic effect in co...

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Detalles Bibliográficos
Autores principales: Saldana-Caboverde, Amy, Nissanka, Nadee, Garcia, Sofia, Lombès, Anne, Diaz, Francisca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599499/
https://www.ncbi.nlm.nih.gov/pubmed/33003371
http://dx.doi.org/10.3390/cells9102197