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Changing Trends in Hospital Admissions for Pulmonary Embolism in Spain from 2001 to 2018

(1) Background: The aims of this study were to examine trends in the incidence, clinical characteristics, and in-hospital outcomes of patients hospitalized with pulmonary embolism in Spain and to identify factors associated with in-hospital mortality (IHM). (2) Methods: We included all patients who...

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Autores principales: de Miguel-Diez, Javier, Albaladejo-Vicente, Romana, Lopez-de-Andres, Ana, Hernández-Barrera, Valentín, Jiménez, David, Monreal, Manuel, Carabantes-Alarcon, David, Zamorano-Leon, José Javier, Jimenez-Garcia, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599502/
https://www.ncbi.nlm.nih.gov/pubmed/33036474
http://dx.doi.org/10.3390/jcm9103221
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author de Miguel-Diez, Javier
Albaladejo-Vicente, Romana
Lopez-de-Andres, Ana
Hernández-Barrera, Valentín
Jiménez, David
Monreal, Manuel
Carabantes-Alarcon, David
Zamorano-Leon, José Javier
Jimenez-Garcia, Rodrigo
author_facet de Miguel-Diez, Javier
Albaladejo-Vicente, Romana
Lopez-de-Andres, Ana
Hernández-Barrera, Valentín
Jiménez, David
Monreal, Manuel
Carabantes-Alarcon, David
Zamorano-Leon, José Javier
Jimenez-Garcia, Rodrigo
author_sort de Miguel-Diez, Javier
collection PubMed
description (1) Background: The aims of this study were to examine trends in the incidence, clinical characteristics, and in-hospital outcomes of patients hospitalized with pulmonary embolism in Spain and to identify factors associated with in-hospital mortality (IHM). (2) Methods: We included all patients who were hospitalized for pulmonary embolism between 2001 and 2018. Data were collected from the Spanish National Hospital Discharge Database. (3) Results: We identified 241,821 hospitalizations for pulmonary embolism during the study period. The incidence of pulmonary embolism increased from 20.49 cases per 100,000 inhabitants in the period 2001–2002 to 35.9 cases in the period 2017–2018 (p < 0.001). After controlling for possible confounders, there was a significant increase in the incidence over the study period (adjusted incidence rate ratio 1.53, 95% Confidence Interval I 1.51–1.56). The median length of hospital stay was 11 days in the period 2001–2002, decreasing to seven days in the period 2017–2018 (p < 0.001). For the total time period, the crude IHM rate was 9.51%. After multivariable adjustment, IHM decreased significantly over time. The IHM was significantly higher in women, in patients suffering from more comorbidities, and in those with a massive pulmonary embolism. (4) Conclusions: Our results revealed an increase in the incidence of pulmonary embolism hospitalizations from 2001 to 2018 in Spain, with older patients being the most affected.
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spelling pubmed-75995022020-11-01 Changing Trends in Hospital Admissions for Pulmonary Embolism in Spain from 2001 to 2018 de Miguel-Diez, Javier Albaladejo-Vicente, Romana Lopez-de-Andres, Ana Hernández-Barrera, Valentín Jiménez, David Monreal, Manuel Carabantes-Alarcon, David Zamorano-Leon, José Javier Jimenez-Garcia, Rodrigo J Clin Med Article (1) Background: The aims of this study were to examine trends in the incidence, clinical characteristics, and in-hospital outcomes of patients hospitalized with pulmonary embolism in Spain and to identify factors associated with in-hospital mortality (IHM). (2) Methods: We included all patients who were hospitalized for pulmonary embolism between 2001 and 2018. Data were collected from the Spanish National Hospital Discharge Database. (3) Results: We identified 241,821 hospitalizations for pulmonary embolism during the study period. The incidence of pulmonary embolism increased from 20.49 cases per 100,000 inhabitants in the period 2001–2002 to 35.9 cases in the period 2017–2018 (p < 0.001). After controlling for possible confounders, there was a significant increase in the incidence over the study period (adjusted incidence rate ratio 1.53, 95% Confidence Interval I 1.51–1.56). The median length of hospital stay was 11 days in the period 2001–2002, decreasing to seven days in the period 2017–2018 (p < 0.001). For the total time period, the crude IHM rate was 9.51%. After multivariable adjustment, IHM decreased significantly over time. The IHM was significantly higher in women, in patients suffering from more comorbidities, and in those with a massive pulmonary embolism. (4) Conclusions: Our results revealed an increase in the incidence of pulmonary embolism hospitalizations from 2001 to 2018 in Spain, with older patients being the most affected. MDPI 2020-10-07 /pmc/articles/PMC7599502/ /pubmed/33036474 http://dx.doi.org/10.3390/jcm9103221 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
de Miguel-Diez, Javier
Albaladejo-Vicente, Romana
Lopez-de-Andres, Ana
Hernández-Barrera, Valentín
Jiménez, David
Monreal, Manuel
Carabantes-Alarcon, David
Zamorano-Leon, José Javier
Jimenez-Garcia, Rodrigo
Changing Trends in Hospital Admissions for Pulmonary Embolism in Spain from 2001 to 2018
title Changing Trends in Hospital Admissions for Pulmonary Embolism in Spain from 2001 to 2018
title_full Changing Trends in Hospital Admissions for Pulmonary Embolism in Spain from 2001 to 2018
title_fullStr Changing Trends in Hospital Admissions for Pulmonary Embolism in Spain from 2001 to 2018
title_full_unstemmed Changing Trends in Hospital Admissions for Pulmonary Embolism in Spain from 2001 to 2018
title_short Changing Trends in Hospital Admissions for Pulmonary Embolism in Spain from 2001 to 2018
title_sort changing trends in hospital admissions for pulmonary embolism in spain from 2001 to 2018
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599502/
https://www.ncbi.nlm.nih.gov/pubmed/33036474
http://dx.doi.org/10.3390/jcm9103221
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