Cargando…
Long-Term Low-Dose Delta-9-Tetrahydrocannbinol (THC) Administration to Simian Immunodeficiency Virus (SIV) Infected Rhesus Macaques Stimulates the Release of Bioactive Blood Extracellular Vesicles (EVs) that Induce Divergent Structural Adaptations and Signaling Cues
Blood extracellular vesicles (BEVs) carry bioactive cargo (proteins, genetic materials, lipids, licit, and illicit drugs) that regulate diverse functions in target cells. The cannabinoid drug delta-9-tetrahydrocannabinol (THC) is FDA approved for the treatment of anorexia and weight loss in people l...
Autores principales: | Lyu, Yuan, Kopcho, Steven, Mohan, Mahesh, Okeoma, Chioma M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599525/ https://www.ncbi.nlm.nih.gov/pubmed/33036231 http://dx.doi.org/10.3390/cells9102243 |
Ejemplares similares
-
Alterations in Abundance and Compartmentalization of miRNAs in Blood Plasma Extracellular Vesicles and Extracellular Condensates during HIV/SIV Infection and Its Modulation by Antiretroviral Therapy (ART) and Delta-9-Tetrahydrocannabinol (Δ(9)-THC)
por: Kopcho, Steven, et al.
Publicado: (2023) -
SIV Infection Regulates Compartmentalization of Circulating Blood Plasma miRNAs within Extracellular Vesicles (EVs) and Extracellular Condensates (ECs) and Decreases EV-Associated miRNA-128
por: Kopcho, Steven, et al.
Publicado: (2023) -
Emergence of resistance mutations in simian immunodeficiency virus (SIV)-infected rhesus macaques receiving non-suppressive antiretroviral therapy (ART)
por: Policicchio, Benjamin Bruno, et al.
Publicado: (2018) -
Chronic delta-9-tetrahydrocannabinol (THC) treatment counteracts SIV-induced modulation of proinflammatory microRNA cargo in basal ganglia-derived extracellular vesicles
por: Kaddour, Hussein, et al.
Publicado: (2022) -
Role of rhesus macaque IFITM3(2) in simian immunodeficiency virus infection of macaques
por: Winkler, Michael, et al.
Publicado: (2019)