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Protective Effects of ALDH1A Enzyme Inhibition on Helicobacter-Induced Colitis in Smad3(−/−) Mice are Associated with Altered α4ß7 Integrin Expression on Activated T Cells
Many inflammatory bowel disease (IBD) patients require surgical intervention due to limited pharmacological treatment options. Antibodies targeting α4ß7, a gut-homing integrin, are one of the most promising IBD treatments. As retinoic acid (RA) regulates expression of gut-homing proteins including α...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599670/ https://www.ncbi.nlm.nih.gov/pubmed/32987910 http://dx.doi.org/10.3390/nu12102927 |