Cargando…
Protective Effect of Geraniol on Oxidative, Inflammatory and Apoptotic Alterations in Isoproterenol-Induced Cardiotoxicity: Role of the Keap1/Nrf2/HO-1 and PI3K/Akt/mTOR Pathways
Background: Myocardial infarction (MI) is still a major contributor to mortality worldwide, and therefore, searching for new drugs is an urgent priority. Natural products are a renewable source for medicinally and pharmacologically active molecules. The objective of this study was to explore the pot...
Autores principales: | Younis, Nancy S., Abduldaium, Mohamed S., Mohamed, Maged E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599734/ https://www.ncbi.nlm.nih.gov/pubmed/33053761 http://dx.doi.org/10.3390/antiox9100977 |
Ejemplares similares
-
Geraniol Averts Methotrexate-Induced Acute Kidney Injury via Keap1/Nrf2/HO-1 and MAPK/NF-κB Pathways
por: Younis, Nancy S., et al.
Publicado: (2021) -
Ameliorative Effect of Linalool in Cisplatin-Induced Nephrotoxicity: The Role of HMGB1/TLR4/NF-κB and Nrf2/HO1 Pathways
por: Mohamed, Maged E., et al.
Publicado: (2020) -
Cardioprotective Effect of Linalool against Isoproterenol-Induced Myocardial Infarction
por: Mohamed, Maged E., et al.
Publicado: (2021) -
Renal Ischemia/Reperfusion Mitigation via Geraniol: The Role of Nrf-2/HO-1/NQO-1 and TLR2,4/MYD88/NFκB Pathway
por: Mohamed, Maged E., et al.
Publicado: (2022) -
α-Bisabolol, a Dietary Sesquiterpene, Attenuates Doxorubicin-Induced Acute Cardiotoxicity in Rats by Inhibiting Cellular Signaling Pathways, Nrf2/Keap-1/HO-1, Akt/mTOR/GSK-3β, NF-κB/p38/MAPK, and NLRP3 Inflammasomes Regulating Oxidative Stress and Inflammatory Cascades
por: Nagoor Meeran, Mohamed Fizur, et al.
Publicado: (2023)