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Preparation of Co-Amorphous Systems by Freeze-Drying

Freeze-drying was evaluated as a production technique for co-amorphous systems of a poorly water-soluble drug. Naproxen was freeze-dried together with arginine and lysine as co-former. To increase the solubility of naproxen in the starting solution, the applicability of five surfactants was investig...

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Detalles Bibliográficos
Autores principales:	Wostry, Melvin, Plappert, Hanna, Grohganz, Holger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599809/ https://www.ncbi.nlm.nih.gov/pubmed/33008124 http://dx.doi.org/10.3390/pharmaceutics12100941

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