Cargando…

DNA Repair Expression Profiling to Identify High-Risk Cytogenetically Normal Acute Myeloid Leukemia and Define New Therapeutic Targets

SIMPLE SUMMARY: Acute myeloid leukemia (AML) is the second most frequent type of adult leukemias. Cytogenetically normal acute myeloid leukemias represent about 50% of total adult AML, exhibit no chromosomal abnormalities, and present high heterogeneity regarding the clinical outcome. Deregulation o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gabellier, Ludovic, Bret, Caroline, Bossis, Guillaume, Cartron, Guillaume, Moreaux, Jérôme
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599826/ https://www.ncbi.nlm.nih.gov/pubmed/33036275 http://dx.doi.org/10.3390/cancers12102874

Ejemplares similares

The NADPH oxidase NOX2 is a marker of adverse prognosis involved in chemoresistance of acute myeloid leukemias
por: Paolillo, Rosa, et al.
Publicado: (2022)

Development of gene expression-based risk score in cytogenetically normal acute myeloid leukemia patients
por: Bou Samra, Elias, et al.
Publicado: (2012)

Ubiquitin and SUMO conjugation as biomarkers of acute myeloid leukemias response to chemotherapies
por: Gâtel, Pierre, et al.
Publicado: (2020)

EZH2 in normal hematopoiesis and hematological malignancies
por: Herviou, Laurie, et al.
Publicado: (2015)

An epigenetic regulator-related score (EpiScore) predicts survival in patients with diffuse large B cell lymphoma and identifies patients who may benefit from epigenetic therapy
por: Szablewski, Vanessa, et al.
Publicado: (2018)

Expression and role of RIP140/NRIP1 in chronic lymphocytic leukemia
por: Lapierre, Marion, et al.
Publicado: (2015)

DeSUMOylation of chromatin-bound proteins limits the rapid transcriptional reprogramming induced by daunorubicin in acute myeloid leukemias
por: Boulanger, Mathias, et al.
Publicado: (2023)

Molecular Mutations and Their Cooccurrences in Cytogenetically Normal Acute Myeloid Leukemia
por: Wang, Mengning, et al.
Publicado: (2017)

Nucleotide excision DNA repair pathway as a therapeutic target in patients with high-risk diffuse large B cell lymphoma
por: Bret, Caroline, et al.
Publicado: (2013)

DNA sequencing of a cytogenetically normal acute myeloid leukemia genome
por: Ley, Timothy J, et al.
Publicado: (2008)

Molecular prognostic markers for adult acute myeloid leukemia with normal cytogenetics
por: Gregory, Tara K, et al.
Publicado: (2009)

Prognostic role of ACTL10 in Cytogenetic Normal Acute Myeloid Leukemia
por: Lai, Rui, et al.
Publicado: (2020)

Acute promyelocytic leukemia relapsing into acute myeloid leukemia-M2 with normal cytogenetics
por: Sahoo, Ranjit Kumar, et al.
Publicado: (2013)

The Prognostic Significance of PDE7B in Cytogenetically Normal Acute Myeloid Leukemia
por: Cao, Ling, et al.
Publicado: (2019)

Wilms Tumor 1 Gene Mutations in Patients with Cytogenetically Normal Acute Myeloid Leukemia
por: Aref, Salah, et al.
Publicado: (2014)

High NCALD expression predicts poor prognosis of cytogenetic normal acute myeloid leukemia
por: Song, Ying, et al.
Publicado: (2019)

Redefining prognostication of de novo cytogenetically normal acute myeloid leukemia in young adults
por: Tsui, Sze P., et al.
Publicado: (2020)

Cytogenetics’ impact on the prognosis of acute myeloid leukemia
por: Gupta, Monika, et al.
Publicado: (2019)

Treatment May Be Harmful: Mechanisms/Prediction/Prevention of Drug-Induced DNA Damage and Repair in Multiple Myeloma
por: Gourzones, Claire, et al.
Publicado: (2019)

PRC2 targeting is a therapeutic strategy for EZ score defined high-risk multiple myeloma patients and overcome resistance to IMiDs
por: Herviou, Laurie, et al.
Publicado: (2018)

Mutation Patterns of 16 Genes in Primary and Secondary Acute Myeloid Leukemia (AML) with Normal Cytogenetics
por: Fernandez-Mercado, Marta, et al.
Publicado: (2012)

High expression of RUNX1 is associated with poorer outcomes in cytogenetically normal acute myeloid leukemia
por: Fu, Lin, et al.
Publicado: (2016)

Prognostic Prediction of Cytogenetically Normal Acute Myeloid Leukemia Based on a Gene Expression Model
por: Yang, Liu, et al.
Publicado: (2021)

Overexpression of Prohibitin 2 Protein is Associated with Adverse Prognosis in Cytogenetically Normal Acute Myeloid Leukemia
por: Lee, Young Eun, et al.
Publicado: (2022)

Residual malignant and normal plasma cells shortly after high dose melphalan and stem cell transplantation. Highlight of a putative therapeutic window in Multiple Myeloma?
por: Caraux, Anouk, et al.
Publicado: (2012)

An uncommon case of chronic myeloid leukemia with variant cytogenetics
por: Abdulla, Mohammad A., et al.
Publicado: (2018)

Overexpression of ATP1B1 predicts an adverse prognosis in cytogenetically normal acute myeloid leukemia
por: Shi, Jin-long, et al.
Publicado: (2015)

KRAS overexpression independent of RAS mutations confers an adverse prognosis in cytogenetically normal acute myeloid leukemia
por: Zhou, Jing-Dong, et al.
Publicado: (2017)

Evaluation of BAALC gene expression in normal cytogenetic acute myeloid leukemia patients in north-east of Iran
por: Amirpour, Mojgan, et al.
Publicado: (2016)

Preventive plasmapheresis for rituximab related flare in cryoglobulinemic vasculitis
por: Fornero, Léa, et al.
Publicado: (2023)

A gene expression profile associated with relapse of cytogenetically normal acute myeloid leukemia is enriched for leukemia stem cell genes
por: Hackl, Hubert, et al.
Publicado: (2015)

TIGAR cooperated with glycolysis to inhibit the apoptosis of leukemia cells and associated with poor prognosis in patients with cytogenetically normal acute myeloid leukemia
por: Qian, Sixuan, et al.
Publicado: (2016)

Cytogenetic profile of Acute Myeloid Leukemia and Acute Lymphoblastic Leukemia in Northern Pakistan
por: Khan, Maria, et al.
Publicado: (2023)

Cytogenetic profile of 1791 adult acute myeloid leukemia in India
por: Srivastava, Vivi M., et al.
Publicado: (2023)

Cytogenetic characteristics of and prognosis for acute myeloid leukemia in 107 children
por: Chen, Wanzi, et al.
Publicado: (2021)

Residual Disease in a Novel Xenograft Model of RUNX1-Mutated, Cytogenetically Normal Acute Myeloid Leukemia
por: Sivagnanalingam, Umayal, et al.
Publicado: (2015)

High expression of MAP7 predicts adverse prognosis in young patients with cytogenetically normal acute myeloid leukemia
por: Fu, Lin, et al.
Publicado: (2016)

MiR-362-5p as a novel prognostic predictor of cytogenetically normal acute myeloid leukemia
por: Ma, Qiu-Ling, et al.
Publicado: (2018)

Association of a cytarabine chemosensitivity related gene expression signature with survival in cytogenetically normal acute myeloid leukemia
por: Yan, Han, et al.
Publicado: (2016)

A 3-miRNA signature predicts prognosis of pediatric and adolescent cytogenetically normal acute myeloid leukemia
por: Zhu, Ruiqi, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_gtaj3lcs2n0hmb08mfudpta3di