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Anti-Human PD-L1 Nanobody for Immuno-PET Imaging: Validation of a Conjugation Strategy for Clinical Translation

Immune checkpoints, such as programmed death-ligand 1 (PD-L1), limit T-cell function and tumor cells use this ligand to escape the anti-tumor immune response. Treatments with monoclonal antibodies blocking these checkpoints have shown long-lasting responses, but only in a subset of patients. This st...

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Detalles Bibliográficos
Autores principales:	Bridoux, Jessica, Broos, Katrijn, Lecocq, Quentin, Debie, Pieterjan, Martin, Charlotte, Ballet, Steven, Raes, Geert, Neyt, Sara, Vanhove, Christian, Breckpot, Karine, Devoogdt, Nick, Caveliers, Vicky, Keyaerts, Marleen, Xavier, Catarina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599876/ https://www.ncbi.nlm.nih.gov/pubmed/33003481 http://dx.doi.org/10.3390/biom10101388

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