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A Second Generation Mn-Porphyrin Dimer with a Twisted Linker as a Potential Blood Pool Agent for MRI: Tuning the Geometry and Binding with HSA

Blood-pool agents (BPAs) are MRI contrast agents (CAs) characterized by their long circulation in the vascular system to provide an extended time window for high-resolution MR angiography (MRA). Prolonged vascular retention, however, impedes the excretion of BPAs. Therefore, chemical strategy to reg...

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Detalles Bibliográficos
Autores principales: Liu, Hanlin, Cheng, Weiran, Dong, Shili, Xu, David Feng, Tang, Keith, Zhang, Xiao-an
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599881/
https://www.ncbi.nlm.nih.gov/pubmed/33003624
http://dx.doi.org/10.3390/ph13100282

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