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Peptide-Based TNF-α-Binding Decoy Therapy Mitigates Lipopolysaccharide-Induced Liver Injury in Mice

A peptide named SEM18, possessing structural similarity to the binding site of tumor necrosis factor (TNF)-α to TNF receptor 1 (TNFR1), was designed. We investigated whether the SEM18 peptide can mitigate lipopolysaccharide (LPS)-induced liver injury in mice. Adult male Balb/cJ mice received LPS (15...

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Detalles Bibliográficos
Autores principales:	Chang, Chao-Yuan, Hsu, Hao-Jen, Foo, Jossen, Shih, Hung-Jen, Huang, Chun-Jen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600127/ https://www.ncbi.nlm.nih.gov/pubmed/33003495 http://dx.doi.org/10.3390/ph13100280

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