Development of Postoperative Pain in Patients with End-Stage Knee Osteoarthritis Is Associated with Upregulation of Genes Related to Extracellular Matrix Degradation, Inflammation, and Apoptosis Measured in the Peripheral Blood before Knee Surgery

Osteoarthritis (OA) pain implies an indication for joint replacement in patients with end-stage OA. However, chronic postoperative pain is observed in 10–40% of patients with OA. Here, we identified genes whose expression in the peripheral blood before surgery could denote the risk of postoperative...

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Autores principales: Tchetina, Elena V., Glemba, Kseniya E., Markova, Galina A., Naryshkin, Evgeniy A., Taskina, Elena A., Makarov, Maksim A., Lila, Aleksandr M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600231/
https://www.ncbi.nlm.nih.gov/pubmed/33007930
http://dx.doi.org/10.3390/life10100224

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