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Completing the Enalaprilat Excretion Pathway—Renal Handling by the Proximal Tubule
Background: Enalapril is often used in the treatment of cardiovascular diseases. Clinical data suggest that the urinary excretion of enalaprilat, the active metabolite of enalapril, is mediated by renal transporters. We aimed to identify enalaprilat specificity for renal proximal tubular transporter...
Autores principales: | Smeets, Nori J. L., Litjens, Carlijn H. C., van den Heuvel, Jeroen J. M. W., van Hove, Hedwig, van den Broek, Petra, Russel, Frans G. M., Koenderink, Jan B., de Wildt, Saskia N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600309/ https://www.ncbi.nlm.nih.gov/pubmed/33007874 http://dx.doi.org/10.3390/pharmaceutics12100935 |
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