Cargando…
The Mutational and Transcriptional Landscapes of Hepatocarcinogenesis in a Rat Model
Hepatocellular carcinoma (HCC) initiation is characterized by stepwise accumulation of molecular alterations, during which the early events are largely unknown. Here, we presented a comprehensive genomic and transcriptomic landscape at stages of hepatitis, cirrhosis, and HCC by using a diethylnitros...
Autores principales: | Chen, Zhiao, Li, Shengli, Shen, Mengting, Lu, Xinyuan, Bao, Chunyang, Chen, Di, Ding, Jie, Wang, Qifeng, Huang, Shenglin, Cong, Wenming, Han, Leng, He, Xianghuo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600387/ https://www.ncbi.nlm.nih.gov/pubmed/33163943 http://dx.doi.org/10.1016/j.isci.2020.101690 |
Ejemplares similares
-
Optimized protocol for an inducible rat model of liver tumor with chronic hepatocellular injury, inflammation, fibrosis, and cirrhosis
por: Chen, Zhiao, et al.
Publicado: (2021) -
RNA Helicase DHX37 Facilitates Liver Cancer Progression by Cooperating with PLRG1 to Drive Superenhancer-Mediated Transcription of Cyclin D1
por: Liu, Zhen, et al.
Publicado: (2022) -
Hepatic SMARCA4 predicts HCC recurrence and promotes tumour cell proliferation by regulating SMAD6 expression
por: Chen, Zhiao, et al.
Publicado: (2018) -
Co-expression of PKM2 and TRIM35 predicts survival and recurrence in hepatocellular carcinoma
por: Chen, Zhiao, et al.
Publicado: (2014) -
Transcriptomic analyses of RNA‐binding proteins reveal eIF3c promotes cell proliferation in hepatocellular carcinoma
por: Li, Tangjian, et al.
Publicado: (2017)