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Moderate SIRT1 overexpression protects against brown adipose tissue inflammation
OBJECTIVE: Metainflammation is a chronic low-grade inflammatory state induced by obesity and associated comorbidities, including peripheral insulin resistance. Brown adipose tissue (BAT), a therapeutic target against obesity, is an insulin target tissue sensitive to inflammation. Therefore, it is ne...
Autores principales: | Escalona-Garrido, Carmen, Vázquez, Patricia, Mera, Paula, Zagmutt, Sebastián, García-Casarrubios, Ester, Montero-Pedrazuela, Ana, Rey-Stolle, Fernanda, Guadaño-Ferraz, Ana, Rupérez, Francisco J., Serra, Dolors, Herrero, Laura, Obregon, Maria Jesus, Valverde, Ángela M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600394/ https://www.ncbi.nlm.nih.gov/pubmed/33049408 http://dx.doi.org/10.1016/j.molmet.2020.101097 |
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