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Moderate SIRT1 overexpression protects against brown adipose tissue inflammation

OBJECTIVE: Metainflammation is a chronic low-grade inflammatory state induced by obesity and associated comorbidities, including peripheral insulin resistance. Brown adipose tissue (BAT), a therapeutic target against obesity, is an insulin target tissue sensitive to inflammation. Therefore, it is ne...

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Detalles Bibliográficos
Autores principales: Escalona-Garrido, Carmen, Vázquez, Patricia, Mera, Paula, Zagmutt, Sebastián, García-Casarrubios, Ester, Montero-Pedrazuela, Ana, Rey-Stolle, Fernanda, Guadaño-Ferraz, Ana, Rupérez, Francisco J., Serra, Dolors, Herrero, Laura, Obregon, Maria Jesus, Valverde, Ángela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600394/
https://www.ncbi.nlm.nih.gov/pubmed/33049408
http://dx.doi.org/10.1016/j.molmet.2020.101097

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