Cargando…

Cancer Predisposition Genes in Cancer-Free Families

SIMPLE SUMMARY: Familial clustering of cancer and identification of high- and low-risk cancer predisposition gene variants implicate that there are families that are at a high to moderate excess risk of cancer. We wanted to test genetically whether there are families protected from cancer. We whole-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Guoqiao, Catalano, Calogerina, Bandapalli, Obul Reddy, Paramasivam, Nagarajan, Chattopadhyay, Subhayan, Schlesner, Matthias, Sijmons, Rolf, Hemminki, Akseli, Dymerska, Dagmara, Lubinski, Jan, Hemminki, Kari, Försti, Asta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600438/ https://www.ncbi.nlm.nih.gov/pubmed/32992489 http://dx.doi.org/10.3390/cancers12102770

Ejemplares similares

Pedigree based DNA sequencing pipeline for germline genomes of cancer families
por: Försti, Asta, et al.
Publicado: (2016)

A rare large duplication of MLH1 identified in Lynch syndrome
por: Kumar, Abhishek, et al.
Publicado: (2021)

Whole exome sequencing identifies novel germline variants of SLC15A4 gene as potentially cancer predisposing in familial colorectal cancer
por: Skopelitou, Diamanto, et al.
Publicado: (2022)

Whole Exome Sequencing Identifies APCDD1 and HDAC5 Genes as Potentially Cancer Predisposing in Familial Colorectal Cancer
por: Skopelitou, Diamanto, et al.
Publicado: (2021)

A Novel Low-Risk Germline Variant in the SH2 Domain of the SRC Gene Affects Multiple Pathways in Familial Colorectal Cancer
por: Skopelitou, Diamanto, et al.
Publicado: (2021)

Identification of Familial Hodgkin Lymphoma Predisposing Genes Using Whole Genome Sequencing
por: Srivastava, Aayushi, et al.
Publicado: (2020)

Second Primary Cancers in Melanoma Patients Critically Shorten Survival
por: Zheng, Guoqiao, et al.
Publicado: (2020)

Types of second primary cancer influence overall survival in cutaneous melanoma
por: Zheng, Guoqiao, et al.
Publicado: (2021)

Whole-Exome Sequencing Identifies a Novel Germline Variant in PTK7 Gene in Familial Colorectal Cancer
por: Miao, Beiping, et al.
Publicado: (2022)

Germline Variants of CYBA and TRPM4 Predispose to Familial Colorectal Cancer
por: Zhu, Lizhen, et al.
Publicado: (2022)

Whole Genome Sequencing Prioritizes CHEK2, EWSR1, and TIAM1 as Possible Predisposition Genes for Familial Non-Medullary Thyroid Cancer
por: Srivastava, Aayushi, et al.
Publicado: (2021)

Familial Cancer Variant Prioritization Pipeline version 2 (FCVPPv2) applied to a papillary thyroid cancer family
por: Kumar, Abhishek, et al.
Publicado: (2018)

Prostate cancer survivors: Risk and mortality in second primary cancers
por: Chattopadhyay, Subhayan, et al.
Publicado: (2018)

Characterization of rare germline variants in familial multiple myeloma
por: Catalano, Calogerina, et al.
Publicado: (2021)

Familial risks of second primary cancers and mortality in ovarian cancer patients
por: Zheng, Guoqiao, et al.
Publicado: (2018)

Familial Risks and Mortality in Second Primary Cancers in Melanoma
por: Chattopadhyay, Subhayan, et al.
Publicado: (2019)

Types of second primary cancers influence survival in chronic lymphocytic and hairy cell leukemia patients
por: Zheng, Guoqiao, et al.
Publicado: (2019)

Multiple myeloma: family history and mortality in second primary cancers
por: Chattopadhyay, Subhayan, et al.
Publicado: (2018)

Second primary cancer after female breast cancer: Familial risks and cause of death
por: Zheng, Guoqiao, et al.
Publicado: (2018)

A Germline Mutation in the POT1 Gene Is a Candidate for Familial Non-Medullary Thyroid Cancer
por: Srivastava, Aayushi, et al.
Publicado: (2020)

Incidence Differences Between First Primary Cancers and Second Primary Cancers Following Skin Squamous Cell Carcinoma as Etiological Clues
por: Zheng, Guoqiao, et al.
Publicado: (2020)

Second Primary Cancers After Gastric Cancer, and Gastric Cancer as Second Primary Cancer
por: Zheng, Guoqiao, et al.
Publicado: (2021)

Rate differences between first and second primary cancers may outline immune dysfunction as a key risk factor
por: Zheng, Guoqiao, et al.
Publicado: (2020)

Second cancers and causes of death in patients with testicular cancer in Sweden
por: Zhang, Luyao, et al.
Publicado: (2019)

Survival in colon and rectal cancers in Finland and Sweden through 50 years
por: Hemminki, Kari, et al.
Publicado: (2021)

Second Primary Cancers After Liver, Gallbladder and Bile Duct Cancers, and These Cancers as Second Primary Cancers
por: Zheng, Guoqiao, et al.
Publicado: (2021)

Whole Genome Sequencing of Familial Non-Medullary Thyroid Cancer Identifies Germline Alterations in MAPK/ERK and PI3K/AKT Signaling Pathways
por: Srivastava, Aayushi, et al.
Publicado: (2019)

Conditional survival in breast cancer up to 10 years in the Nordic countries
por: Zitricky, Frantisek, et al.
Publicado: (2023)

Survival, Incidence, and Mortality Trends in Female Cancers in the Nordic Countries
por: Tichanek, Filip, et al.
Publicado: (2023)

Survival in Lung Cancer in the Nordic Countries Through A Half Century
por: Tichanek, Filip, et al.
Publicado: (2023)

Conditional Survival in Prostate Cancer in the Nordic Countries Elucidates the Timing of Improvements
por: Zitricky, Frantisek, et al.
Publicado: (2023)

Long-term survival trends for primary liver and pancreatic cancers in the Nordic countries
por: Hemminki, Kari, et al.
Publicado: (2022)

Survival in gastric and esophageal cancers in the Nordic countries through a half century
por: Hemminki, Kari, et al.
Publicado: (2023)

Cervical, vaginal and vulvar cancer incidence and survival trends in Denmark, Finland, Norway and Sweden with implications to treatment
por: Hemminki, Kari, et al.
Publicado: (2022)

Survival in bladder and upper urinary tract cancers in Finland and Sweden through 50 years
por: Hemminki, Kari, et al.
Publicado: (2022)

Survival in Kidney and Bladder Cancers in Four Nordic Countries through a Half Century
por: Tichanek, Filip, et al.
Publicado: (2023)

Long-Term Periodic and Conditional Survival Trends in Prostate, Testicular, and Penile Cancers in the Nordic Countries, Marking Timing of Improvements
por: Tichanek, Filip, et al.
Publicado: (2023)

Incidence trends in bladder and lung cancers between Denmark, Finland and Sweden may implicate oral tobacco (snuff/snus) as a possible risk factor
por: Hemminki, Kari, et al.
Publicado: (2021)

Informing patients about their mutation tests: CDKN2A c.256G>A in melanoma as an example
por: Hemminki, Kari, et al.
Publicado: (2020)

Bladder and upper urinary tract cancers as first and second primary cancers
por: Zheng, Guoqiao, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_j45p3bvl8oe0gt3kuperbak013