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Amphiphilic “Like-A-Brush” Oligonucleotide Conjugates with Three Dodecyl Chains: Self-Assembly Features of Novel Scaffold Compounds for Nucleic Acids Delivery

The conjugation of lipophilic groups to oligonucleotides is a promising approach for improving nucleic acid-based therapeutics’ intracellular delivery. Lipid oligonucleotide conjugates can self-aggregate in aqueous solution, which gains much attention due to the formation of micellar particles suita...

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Detalles Bibliográficos
Autores principales:	Pavlova, Anna S., Dovydenko, Ilya S., Kupryushkin, Maxim S., Grigor’eva, Alina E., Pyshnaya, Inna A., Pyshnyi, Dmitrii V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600535/ https://www.ncbi.nlm.nih.gov/pubmed/33003636 http://dx.doi.org/10.3390/nano10101948

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