Cargando…

Fertility Preservation in Childhood Cancer: Endocrine Activity in Prepubertal Human Testis Xenografts Exposed to a Pubertal Hormone Environment

SIMPLE SUMMARY: Substantial strides have been made in treating childhood cancers; however, as a result of chemotherapy and radiotherapy, young males experience long-term side effects, including impaired fertility. Whilst prepubertal testicular tissue can be cryopreserved prior to gonadotoxic treatme...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hutka, Marsida, Kadam, Prashant, Van Saen, Dorien, Homer, Natalie Z. M., Onofre, Jaime, Wallace, W. Hamish B., Smith, Lee B., Stukenborg, Jan-Bernd, Goossens, Ellen, Mitchell, Rod T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600569/ https://www.ncbi.nlm.nih.gov/pubmed/33008013 http://dx.doi.org/10.3390/cancers12102830

Ejemplares similares

Exogenous Gonadotrophin Stimulation Induces Partial Maturation of Human Sertoli Cells in a Testicular Xenotransplantation Model for Fertility Preservation
por: Hutka, Marsida, et al.
Publicado: (2020)

Cancer treatment in childhood and testicular function: the importance of the somatic environment
por: Stukenborg, Jan-Bernd, et al.
Publicado: (2018)

Does co-transplantation of mesenchymal and spermatogonial stem cells improve reproductive efficiency and safety in mice?
por: Kadam, Prashant, et al.
Publicado: (2019)

Differentiation of Testis Xenografts in the Prepubertal Marmoset Depends on the Sex and Status of the Mouse Host
por: Sharma, Swati, et al.
Publicado: (2018)

How does chemotherapy treatment damage the prepubertal testis?
por: Allen, Caroline M, et al.
Publicado: (2018)

Microbiological findings in prepubertal and pubertal girls with vulvovaginitis
por: Baka, Stavroula, et al.
Publicado: (2022)

Sexual maturation and fertility of mice exposed to triphenyltin during prepubertal and pubertal periods
por: Mello, Marcia S. Campos, et al.
Publicado: (2014)

Xenografting of human fetal testis tissue: a new approach to study fetal testis development and germ cell differentiation
por: Mitchell, Rod T., et al.
Publicado: (2010)

Factors affecting prepubertal and pubertal bone age progression
por: Satoh, Mari, et al.
Publicado: (2022)

Complete spermatogenesis in intratesticular testis tissue xenotransplants from immature non-human primate
por: Ntemou, E, et al.
Publicado: (2019)

In search of the most efficient fertility preservation strategy for prepubertal boys
por: Van Saen, D.
Publicado: (2013)

Diethylstilboestrol Exposure Does Not Reduce Testosterone Production in Human Fetal Testis Xenografts
por: Mitchell, Rod T., et al.
Publicado: (2013)

Co-transplantation of mesenchymal stem cells improves spermatogonial stem cell transplantation efficiency in mice
por: Kadam, Prashant, et al.
Publicado: (2018)

Human Fetal Testis Xenografts Are Resistant to Phthalate-Induced Endocrine Disruption
por: Heger, Nicholas E, et al.
Publicado: (2012)

Analysis of MicroRNA Expression in the Prepubertal Testis
por: Buchold, Gregory M., et al.
Publicado: (2010)

In vitro maturation and fertilization of prepubertal and pubertal black Bengal goat oocytes
por: Khatun, Momena, et al.
Publicado: (2011)

The Effect of a Unilateral Orchiectomy before Gonadotoxic Treatment on the Contralateral Testis in Adult and Prepubertal Rats
por: Rombaut, Charlotte, et al.
Publicado: (2016)

Irinotecan metabolite SN38 results in germ cell loss in the testis but not in the ovary of prepubertal mice
por: Lopes, Federica, et al.
Publicado: (2016)

The effects of prepubertal epididymal ligation upon the rat testis
por: Gur, Fatih Mehmet, et al.
Publicado: (2014)

Abnormal histology in testis from prepubertal boys with monorchidism
por: Hadziselimovic, Faruk, et al.
Publicado: (2020)

Disorders of Puberty: Endocrinology of the Pre-Pubertal Testis
por: La Vignera, Sandro, et al.
Publicado: (2020)

Rebuilding the human testis in vitro
por: Oliver, E., et al.
Publicado: (2019)

Prepubertal unilateral gynecomastia in the absence of endocrine abnormalities
por: Kang, Min, et al.
Publicado: (2014)

Chemotherapy drugs cyclophosphamide, cisplatin and doxorubicin induce germ cell loss in an in vitro model of the prepubertal testis
por: Smart, Ellie, et al.
Publicado: (2018)

Association of prepubertal obesity with pubertal development in Chinese girls and boys: A longitudinal study
por: Li, Wenyan, et al.
Publicado: (2018)

TSPAN8 Expression Distinguishes Spermatogonial Stem Cells in the Prepubertal Mouse Testis
por: Mutoji, Kazadi, et al.
Publicado: (2016)

Serum Kisspeptin and Its Relation to Metabolic Parameters and Glucose Metabolism in Prepubertal and Pubertal Obese Children
por: Sithinamsuwan, Kochakorn, et al.
Publicado: (2020)

Effects of Environmental Endocrine Disruptors on Pubertal Development
por: Özen, Samim, et al.
Publicado: (2011)

Endocrine disrupter effects on the gonads and pubertY
por: Söder, Olle
Publicado: (2013)

Insulin Resistance in Obese Children and Adolescents: HOMA−IR Cut−Off Levels in the Prepubertal and Pubertal Periods
por: Kurtoğlu, Selim, et al.
Publicado: (2010)

A Prospective Cohort Study Investigating the Impact of Neutering Bitches Prepubertally or Post-Pubertally on Physical Development
por: Moxon, Rachel, et al.
Publicado: (2023)

Testis-Sparing Surgery for Non-Palpable Leydig Cell Tumors in Prepubertal Children
por: Lambropoulos, Vassilis, et al.
Publicado: (2020)

Endocrine disruptors and testis development.
por: Sharpe, R M, et al.
Publicado: (1998)

Decreased spermatogonial quantity in prepubertal boys with leukaemia treated with alkylating agents
por: Poganitsch-Korhonen, M, et al.
Publicado: (2017)

An unanswered question in pediatric urology: the post pubertal persistence of prepubertal congenital penile curvature correction by tunical plication
por: Ozkuvanci, Ünsal, et al.
Publicado: (2017)

Importance of the Androgen Receptor Signaling in Gene Transactivation and Transrepression for Pubertal Maturation of the Testis
por: Edelsztein, Nadia Y., et al.
Publicado: (2019)

Cisplatin Effects on the Human Fetal Testis – Establishing the Sensitive Period for (Pre)Spermatogonial Loss and Relevance for Fertility Preservation in Pre-Pubertal Boys
por: Matilionyte, Gabriele, et al.
Publicado: (2022)

Re: An unanswered question in pediatric urology: the post pubertal persistence of prepubertal congenital penile curvature correction by tunical plication
por: Yachia, Daniel
Publicado: (2018)

Effects of heat stress on endocrine functions & behaviour in the pre-pubertal rat
por: Mete, Fatih, et al.
Publicado: (2012)

Endocrine and pubertal disturbances in optic nerve hypoplasia, from infancy to adolescence
por: Oatman, Oliver J, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_8gvr8opkh6ijqdqldoc9vbe8fd