High NRF2 Levels Correlate with Poor Prognosis in Colorectal Cancer Patients and with Sensitivity to the Kinase Inhibitor AT9283 In Vitro

Aberrant hyperactivation of nuclear factor erythroid 2 (NF-E2) p45-related factor 2 (NRF2) is a common event in many tumour types and associates with resistance to therapy and poor patient prognosis; however, its relevance in colorectal tumours is not well-established. Measuring the expression of su...

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Detalles Bibliográficos
Autores principales: Torrente, Laura, Maan, Gunjit, Oumkaltoum Rezig, Asma, Quinn, Jean, Jackson, Angus, Grilli, Andrea, Casares, Laura, Zhang, Ying, Kulesskiy, Evgeny, Saarela, Jani, Bicciato, Silvio, Edwards, Joanne, Dinkova-Kostova, Albena T., de la Vega, Laureano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600603/
https://www.ncbi.nlm.nih.gov/pubmed/32992842
http://dx.doi.org/10.3390/biom10101365

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