XPO1(E571K) Mutation Modifies Exportin 1 Localisation and Interactome in B-Cell Lymphoma

SIMPLE SUMMARY: Almost 25% of patients with either primary mediastinal B-cell lymphoma (PMBL) or classical Hodgkin lymphoma (cHL) possess a recurrent mutation of the XPO1 gene encoding the major nuclear export protein. The aim of our study was to assess the molecular function of the mutant XPO1 prot...

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Detalles Bibliográficos
Autores principales: Miloudi, Hadjer, Bohers, Élodie, Guillonneau, François, Taly, Antoine, Gibouin, Vincent Cabaud, Viailly, Pierre-Julien, Jego, Gaëtan, Grumolato, Luca, Jardin, Fabrice, Sola, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600770/
https://www.ncbi.nlm.nih.gov/pubmed/33007990
http://dx.doi.org/10.3390/cancers12102829

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