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Increased Expression of NPM1 Suppresses p27(Kip1) Function in Cancer Cells

SIMPLE SUMMARY: Cancer malignancy frequently correlates with a low expression of p27(Kip1), a major cyclin-dependent kinase inhibitor, and the p27 protein level has been reportedly responsible for its antiproliferative function. However, we found the function of overexpressed p27 is suppressed in so...

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Detalles Bibliográficos
Autores principales:	Kometani, Tatsuya, Arai, Takuya, Chibazakura, Taku
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600800/ https://www.ncbi.nlm.nih.gov/pubmed/33050036 http://dx.doi.org/10.3390/cancers12102886

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