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Trajectories of Hospitalization in COVID-19 Patients: An Observational Study in France
Describing the characteristics of COVID-19 patients in the hospital is of importance to assist in the management of hospital capacity in the future. Here, we analyze the trajectories of 1321 patients admitted to hospitals in northern and eastern France. We found that the time from onset to hospitali...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600846/ https://www.ncbi.nlm.nih.gov/pubmed/33003375 http://dx.doi.org/10.3390/jcm9103148 |
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author | Boëlle, Pierre-Yves Delory, Tristan Maynadier, Xavier Janssen, Cécile Piarroux, Renaud Pichenot, Marie Lemaire, Xavier Baclet, Nicolas Weyrich, Pierre Melliez, Hugues Meybeck, Agnès Lanoix, Jean-Philippe Robineau, Olivier |
author_facet | Boëlle, Pierre-Yves Delory, Tristan Maynadier, Xavier Janssen, Cécile Piarroux, Renaud Pichenot, Marie Lemaire, Xavier Baclet, Nicolas Weyrich, Pierre Melliez, Hugues Meybeck, Agnès Lanoix, Jean-Philippe Robineau, Olivier |
author_sort | Boëlle, Pierre-Yves |
collection | PubMed |
description | Describing the characteristics of COVID-19 patients in the hospital is of importance to assist in the management of hospital capacity in the future. Here, we analyze the trajectories of 1321 patients admitted to hospitals in northern and eastern France. We found that the time from onset to hospitalization decreased with age, from 7.3 days in the 20–65 year-olds to 4.5 in the >80 year-olds (p < 0.0001). Overall, the length of stay in the hospital was 15.9 days, and the death rate was 20%. One patient out of four was admitted to the intensive care unit (ICU) for approximately one month. The characteristics of trajectories changed with age: fewer older patients were admitted to the ICU and the death rate was larger in the elderly. Admission shortly after onset was associated with increased mortality (odds-ratio (OR) = 1.8, Confidence Interval (CI) 95% [1.3, 2.6]) as well as male sex (OR = 2.1, CI 95% [1.5, 2.9]). Time from admission within the hospital to the transfer to ICU was short. The age- and sex-adjusted mortality rate decreased over the course of the epidemic, suggesting improvement in care over time. In the SARS-CoV-2 epidemic, the urgent need for ICU at admission and the prolonged length of stay in ICU are a challenge for bed management and organization of care. |
format | Online Article Text |
id | pubmed-7600846 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-76008462020-11-01 Trajectories of Hospitalization in COVID-19 Patients: An Observational Study in France Boëlle, Pierre-Yves Delory, Tristan Maynadier, Xavier Janssen, Cécile Piarroux, Renaud Pichenot, Marie Lemaire, Xavier Baclet, Nicolas Weyrich, Pierre Melliez, Hugues Meybeck, Agnès Lanoix, Jean-Philippe Robineau, Olivier J Clin Med Article Describing the characteristics of COVID-19 patients in the hospital is of importance to assist in the management of hospital capacity in the future. Here, we analyze the trajectories of 1321 patients admitted to hospitals in northern and eastern France. We found that the time from onset to hospitalization decreased with age, from 7.3 days in the 20–65 year-olds to 4.5 in the >80 year-olds (p < 0.0001). Overall, the length of stay in the hospital was 15.9 days, and the death rate was 20%. One patient out of four was admitted to the intensive care unit (ICU) for approximately one month. The characteristics of trajectories changed with age: fewer older patients were admitted to the ICU and the death rate was larger in the elderly. Admission shortly after onset was associated with increased mortality (odds-ratio (OR) = 1.8, Confidence Interval (CI) 95% [1.3, 2.6]) as well as male sex (OR = 2.1, CI 95% [1.5, 2.9]). Time from admission within the hospital to the transfer to ICU was short. The age- and sex-adjusted mortality rate decreased over the course of the epidemic, suggesting improvement in care over time. In the SARS-CoV-2 epidemic, the urgent need for ICU at admission and the prolonged length of stay in ICU are a challenge for bed management and organization of care. MDPI 2020-09-29 /pmc/articles/PMC7600846/ /pubmed/33003375 http://dx.doi.org/10.3390/jcm9103148 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Boëlle, Pierre-Yves Delory, Tristan Maynadier, Xavier Janssen, Cécile Piarroux, Renaud Pichenot, Marie Lemaire, Xavier Baclet, Nicolas Weyrich, Pierre Melliez, Hugues Meybeck, Agnès Lanoix, Jean-Philippe Robineau, Olivier Trajectories of Hospitalization in COVID-19 Patients: An Observational Study in France |
title | Trajectories of Hospitalization in COVID-19 Patients: An Observational Study in France |
title_full | Trajectories of Hospitalization in COVID-19 Patients: An Observational Study in France |
title_fullStr | Trajectories of Hospitalization in COVID-19 Patients: An Observational Study in France |
title_full_unstemmed | Trajectories of Hospitalization in COVID-19 Patients: An Observational Study in France |
title_short | Trajectories of Hospitalization in COVID-19 Patients: An Observational Study in France |
title_sort | trajectories of hospitalization in covid-19 patients: an observational study in france |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600846/ https://www.ncbi.nlm.nih.gov/pubmed/33003375 http://dx.doi.org/10.3390/jcm9103148 |
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